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Biohacking

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Key Takeaways Elysium is a life sciences startup that develops consumer-oriented health products based on scientific aging and longevity research.Their first product is Basis, a science-based supplement that promotes health and longevity at the cellular level. Basis was designed and manufactured according to the latest scientific discoveries in the field of anti-aging—namely on the importance of sirtuins and nicotinamide adenine dinucleotide (NAD).Sirtuins are the so-called ”anti-aging genes” that get less active as we age. Reactivating…

Key Takeaways The thymus (an essential organ of the immune system) withers away with age. This is called ”thymic involution”Thymic involution gradually leads to the collapse of a person’s T-cell potential, resulting in a drastic increase in the incidence of cancer, autoimmune disorders, atherosclerosis, systemic inflammation, and mortality in generalGrowth hormone injections restore thymus structure and improve its functionThese changes are accompanied by a reversal of epigenetic aging, leading to a 2-year boost in life…

Introducing David Sinclair, The Einstein of Longevity? David Sinclair just came out with a book, Lifespan. He’s one of the experts I’ve been following most closely in longevity, next to Peter Attia and Aubrey de Grey, due to his extensive list of accomplishments across disciplines, all tunnel-visioned towards this problem. He’s been heads-down on solving aging for over thirty years, as a professor and published researcher at Harvard, co-founder of the journal Aging, co-founder of…

Key Takeaways Nicotinamide adenine dinucleotide (NAD+) is an essential compound for optimal function of all systems in the bodyAging is accompanied by a universal decrease in NAD+ levels in the body despite the body’s need for NAD+ increasing with ageMany age-related conditions have been linked to NAD+ deficiencyImproving NAD+ production and replenishing NAD+ levels in the body may promote health and longevity Actions to Consider You can replenish your NAD+ levels by taking a supplement…

Key Takeaways Suppressing the TOR (target of rapamycin) enzyme in insects, worms, and other invertebrates leads to an increase in their lifespanIt was unclear if this lifespan-extending effect would be observed after suppressing the mTOR (mammalian target of rapamycin) enzyme in mammaliansThe current study reported that male mice fed with rapamycin had a 9% improvement in their expected 90% mortality age (the age at which 90% of mice would be dead from natural causes) while…

Key Takeaways Glutathione is a well-known antioxidant and detoxifying compoundGlutathione levels significantly decrease with age, causing many age-related disordersLow doses of N-acetyl-cysteine (NAC), another detoxifying compound, can increase glutathione levels and prevent the detrimental changes linked to its decline. In theory, NAC could promote longevity in humans Actions to Consider NAC is available as an inexpensive over-the-counter supplement. Daily doses ranging from 600 to 1,800 mg per day seem to be safe and effective in…

Key Takeaways Cold temperatures increase lifespan by 10-20% in animal studiesThe life-extending effect of cold environments is caused by an activation of specific longevity genesThis relationship is an example of hormesis—paradoxical adaptation in which an organism lives longer in unfavorable life conditions Actions to Consider A cold environment could promote your longevity. Embrace cold showers, try a Cryotherapy chamber, go for a walk in brisk weather, or trade the beach for a ski trip!Not a…

Key Takeaways Oxidized nicotinamide adenine dinucleotide (NAD+) is an essential resource for the optimal function of the mitochondriaSupplementing mice with nicotinamide riboside (NR), a precursor of NAD+, prevented muscle degeneration and enhanced muscle function in the treated animalsNR also delayed the aging of stem cells in mice, resulting in an increase in lifespan Actions to Consider Increasing your NAD+ levels could be beneficial for your lifespan and healthspanAlthough more studies are needed to confirm the…

Key Takeaways New science is revealing that aging is not something we have to accept and endure, but a condition that we can reverseAging may be caused by an impairment of epigenetic information in the body, essentially meaning that we “forget how to be young”Advanced technologies are already showing encouraging results in reversing aging in animal studies by restoring the integrity of epigenetic information Actions to Consider The human body has built-in defense mechanisms and…