Key Takeaways

  • Elysium is a life sciences startup that develops consumer-oriented health products based on scientific aging and longevity research.
  • Their first product is Basis, a science-based supplement that promotes health and longevity at the cellular level. Basis was designed and manufactured according to the latest scientific discoveries in the field of anti-aging—namely on the importance of sirtuins and nicotinamide adenine dinucleotide (NAD).
  • Sirtuins are the so-called ”anti-aging genes” that get less active as we age. Reactivating the sirtuins has been confirmed to reverse aging and promote health.
  • Activated sirtuins heavily rely on nicotinamide adenine dinucleotide (NAD) for fuel.
  • Clinical studies have confirmed the effectiveness of Elysium’s Basis in increasing the level of nicotinamide adenine dinucleotide (NAD),

This startup aims to pack youth into pills

Elysium is a young startup with an ambitious goal: to create the first scientifically confirmed and clinically tested longevity supplement.

So far, they seem to be doing well, with a clinical study in 2017 reporting the effectiveness of their first product, Basis.

But how does it work? Is it really possible to pack youth into pills?

The science behind Basis

To understand how Elysium’s Basis works, let’s start with the basics: sirtuins and NAD. 

Sirtuins are commonly referred to as the longevity genes. For a more detailed overview, read our post on David Sinclair’s work.

Sirtuin activity naturally declines with age, and when scientists manage to reactivate these genes, they usually see amazing results regardless of the study model or host species. Allegedly, animals with activated sirtuins live to what equals 120 years in humans, they aren’t affected by cancer, and they don’t gain excess weight.

One natural sirtuin activator is resveratrol, a polyphenol found in the skin of dark berries and grapes (that’s why it’s also present in wine). Pterostilbene is a molecule similar to resveratrol—with quite a few extra features. Although it’s present in much lower doses in fruits and berries, pterostilbene is more stable and much more bioavailable.

Once the sirtuins are activated, they rely on nicotinamide adenine dinucleotide (NAD) as fuel. NAD is a signaling molecule that takes part in regulating all processes in the body, including those related to aging—or anti-aging, in this case. NAD levels decline with age.

One serving of Basis contains 50 mg of pterostilbene as a sirtuin activator and 250 mg of nicotinamide riboside as a NAD precursor. The synergistic action of these two anti-aging compounds is what defines the potential of Basis as an anti-aging supplement.

Specifically, the study published in 2017 on the effectiveness of Basis reported a 40% average increase in NAD levels throughout the first month of supplementation.

This may be relevant for adding more years, but that’s only a piece of the goal.

It’s not only a matter of age

Eric Marcotulli, the co-founder of Elysium, emphasizes that there are many health issues that science and medicine will have to tackle, especially when we find effective anti-aging solutions.

He illustrates this with an anecdote.

Imagine you enter a room full of people of all ages and ask them two questions:

1) How long do they want to live? Forever? 150 years? 80 years?

2) Would they still want to live to this age if they’re going to reach it in their current health?

As it turns out, the second question is even more important than the first one, and many people change their first answer.

After all, what is the point of living longer if your health won’t be up for the challenge?

That’s why Elysium as a company focuses more on healthspan than lifespan, even though the beneficial effects of their Basis supplement are likely to promote both.


So far, we’re bullish on Elysium’s progress and mission. Basis is available on a subscription model for US residents at $50 per month or $480 per year, with one bottle of 60 supplements (30 servings) delivered every month.

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